DeepDx Prostate – RP (Radical Prostatectomy) detects tumor areas on radical prostatectomy WSIs. Diagnostic information such as tumor classification and quantification are automatically determined, resulting in a Gleason Score and ISUP (International Society of Urological Pathology) grade group and tumor segmentations.
Tested by Professionals
In an external validation study, the algorithm achieved an overall high agreement with the reference standard created by the consensus of the two uropathologists, with quadratic weighted kappa of 0.79.
It performed especially well at clinically meaningful thresholds in evaluating benign vs malignant (κ 0.927), and clinically low-risk (benign, GG 1-2) versus high-risk (GG 3-5) disease (κ 0.858).
In another study, the algorithm achieved an IoU of 0.8 for cancer coverage.
* All kappa results were measured at the patch level.